The Cancer Therapy & Research Center (CTRC)
at the University of Texas Health Science Center at San Antonio

Cancer Development and Progression Pilot Grant Program

Deadline: 11:59 pm Monday, June 2, 2008


As members of the Cancer Development and Progression Program you are invited to submit applications for pilot grant funding. The purpose of this funding mechanism is to support collaborative research among members that has the potential for attracting extramural (especially NCI) funding.

GUIDELINES:

1. The proposed research must be a new collaborative project amongst two or more Cancer Center investigators; at least one researcher must be a primary member of the CDP Program.

2. The applications must be responsive to the objectives of one of the four themes identified below; please designate the appropriate theme or themes on the grant application cover page.

Aging and Cancer
Contact for additional information: Peter Hornsby (Hornsby@uthscsa.edu; 2-5080)
Aims: Aging is the largest risk factor for cancer. Major research questions - what are the mechanisms?
There are three areas of focus:
(a.) Cellular mechanisms that protect DNA, proteins and lipids from damage may increase life span and result in resistance to cancer development:
-- within a species; as a function of genetics/environment
-- across species; comparative biology approach
(b.) Age changes in the immune system, endocrine system, and control of stem cells, result in increased susceptibility to cancer and accelerated cancer development
(c.) Cellular aging (senescence) and apoptosis act in pathways that prevent or promote cancer.

Chronic Inflammation and Cancer
Contact for additional information: S.J. Gao (gaos@uthscsa.edu; 2-9030)
Facilitates inter- and intra-programmatic collaborative research on inflammation, infection, immunity and microenvironments that are related to cancer development and progression.

Genomic Integrity
Contacts for additional information: Z. Dave Sharp (sharp@uthscsa.edu; 7-7226); E. Paul Hasty (hastye@uthscsa.edu; 7-7278)
Supports intra-thematic collaborative research programs among members directed toward cellular responses to genomic damage.

Women's Cancer
Contact for additional information: Rajeshware Rao Tekmal (Tekmal@uthscsa.edu; 7-4935).
Focuses on three areas (Breast, Cervical, and ovarian cancers). Research projects with good translational potential and are specific to breast, cervical, and ovarian cancers will be considered. Funds should be used to develop preliminary data necessary to obtain federal funding.

3. Proposals may request funds up to $50K; however, the final funding level will be determined based on the number of proposals with high priority scores. Funds should not be used for faculty salaries or for travel. Scientific reviews by a Cancer Center panel of experts. Programmatic review will be conducted by the theme Leaders and Co-Leaders, and final funding decisions will be made based on both scientific merit and overall goals of the CDP program.

4. Applications must be received by 11:59 PM, Monday, June 2, 2008.

APPLICATION:

The application instructions, forms, and proposal upload site can be accessed below. Please refer back to this website for any future submissions as instructions, guidelines, coversheets, and forms may be revised.

Questions regarding programmatic issues can be directed to Diana Hottle at 567-7204, hottle@uthscsa.edu.

Please submit the following:

Certification of Proposal (COP)
Summary abstract (maximum 1 page)
Scientific plan (maximum 3 single-spaced pages) organized as follows: Background, Significance and Experimental Plan
Include statement of synergy of the collaborating investigator and how it will facilitate or greatly accelerate fundable research that would not be achievable through the efforts of a single laboratory.
Optional: Tables, figures and legends (maximum 2 pages)
Literature citations
Budget & Budget Justification for first year (use NIH form – NOT the modular format)
Plan for seeking outside grant support including specific agencies and timetable.
Applicant's biographical sketch (use NIH format)
Other Support (use NIH format)

Pilot Program Cover Page


Please direct any questions regarding the upload system to Pepper Cumming in the Office of Sponsored Programs, 567-2330, cumming@uthscsa.edu

  1. Applications should be uploaded as a PDF file by 11:59 p.m. on the deadline date to the HSC Sponsored Programs Proposal Upload System.
  2. You must use Internet Explorer to enter the upload system.
  3. Please try to access the upload system before the deadline date (between the hours of 8 am and 5 pm) so that any log-in problems can be addressed.
  4. After uploading your document please wait: you will get a confirmation on your computer screen that your application was uploaded successfully.
  5. Applications that you have uploaded for the current deadline cycle can be viewed simply by logging into the upload system and clicking on the link to -step 2- View your proposals and/or upload proposal document.

    - Please continue to the Sponsored Programs Proposal Upload System by clicking the link below:

    https://adminweb.uthscsa.edu/GrantPro/GMProphome.asp

    You will need to "log in" using your HSC domain or NT username and password . If the "log in" box only asks for username and password you should enter your username as follows: uthscsa\username
     

    additional "log in" username and password information

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