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PHS 398 Application Instructions, Forms, Additional Notices and Information for Preparing an NIH Grant Application. The PHS 398 is used primarily by the NIH to apply for All new, competing, revised, and supplemental grants, regardless of funding mechanism (with the exception of the Individual National Research Service Award training grants). The PHS 398 is also widely used, in whole and part, by other federal and private agencies as well.

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The notices included on this page are important in preparing a proposal. Information is updated and notices are revised periodically; therefore, it is essential that applicants review the additional information before preparing an application for any items or issues that could affect the acceptance and review of his/her application.

CONTENTS:

	PHS 398 (rev. 11/07)     instructions    forms   PHS 398 face page   HSC PHS 398 form page 5 - Customized Budget (HSC internal form to be used when applying for NIH Modular Grants)   NIH address mailing label  398 PI Assurance for New, Renewal, and Revised Applications to NIH UTHSCSA Effort to Person Month Conversion New! NIH Submission Schedule and Transition Dates
	NIH Standard Due Dates for Competing Applications
	Certification of Proposal- COP In order to provide your proposal with signature, Sponsored Programs needs a completed and signed COP with the necessary approvals and approval letters (humans, animals, safety). COP Instructions and Definitions
	Proposal Review & Submission Guide Instructions to follow when submitting a proposal to the HSC Office of Sponsored Programs for review and signature.
	Face Page and Proposal Information F&A rate, DHHS agreement date, assurance numbers and other information commonly requested in research grant applications.
	Type size and format specifications (Part I, page 17 of PHS 398 instructions) Type Size Requirement Sample
	Guide to Converting Word Files to Adobe Acrobat
	Budget Info. Budget Development -information on Budget and Cost Guidelines that includes information on salaries and expendable materials and supplies. F & A Calculation HSC Procedures for Modular Grant Applications Use the modular grant format for proposals requesting direct costs of $250,000 or less or when the modular grant format is required by a particular RFA. NIH Salary Cap. The current salary cap is $191,300; however, NIH reminds us that actual salaries should be used in the proposal budget and NIH will make the appropriate changes with regards to Salary Cap at time of award. It should be noted that if the salary cap is used as the base salary rather than the institutional salary and the salary cap is raised the PI will not benefit from the salary increase. (NIH Guide announcement: SALARY LIMITATION ON GRANTS, COOPERATIVE AGREEMENTS AND CONTRACTS (NOT-OD-08-035) Inflation rate. NIH allows for a yearly maximum inflation rate of 3%. Capital Equipment. The HSC equipment capitalization threshold is $5,000. This means that each item of equipment that costs less than $5,000 should be shown in the materials and supplies line of your budgets and that you will need to include them in your calculation of F&A (indirect) costs.
	Humans and Animals as Research Subjects NIH-IRB and IACUC review and approval is not required at proposal time. Additional information on NIH - IRB and IACUC review and approvals While IRB approval is not needed at NIH proposal submission time there are Human Subjects issues that must be addressed in the Human Subjects Research Section of the Research Design and Methods section of the proposal. Please see pages 18-22 of the PHS 398 instructions for guidance on this issue. IRB Human Subjects Education Requirements IACUC
	Memorandum of Understanding (MoU) For faculty having VA Appointments as Investigators on Grants and Contracts MOU Form Guidance for Calculation of Salaries of Personnel With VA Appointments
	Copies of Submitted Proposals. Sponsored Programs needs a copy of the proposal within five days of its submission.