Proposals can be submitted electronically through the Grants.gov portal. Cayuse424 is a web-based application, specifically designed for preparing, managing, and submitting grant applications. It contains many Federal research forms and supports Grant Mechanisms accepted by NIH and other agencies that use the SF424 and SF424 Research & Related forms. Cayuse424 not only contains all the forms necessary for the detailed budgets, but budgetary computations are performed automatically. Everything you enter is stored and retrievable at a later date.