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© 1997-2005
Updated 02 May 2005.
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Updated 15 July 2005


Department of Laboratory Animal Resources - Medical Care

Use of Analgesics, Tranquilizers, and Anesthetic Agents in Laboratory Animals

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 Sheep/Goat Anesthesia
Anesthesia
Concentration
Dose and Route
Onset
Duration of Surgical Anesthesia
Goat Cocktail 
Ketamine 47.6/ml
Xylazine 4.8mg/ml
Acepromazine 4.8mg/ml
1ml/60lbs IM
5-10 minutes
30-45 minutes
Isoflurane
induction 4-5%
maintenance 1-2%
Inhalation
2-3 minutes
until disconnected
Halothane
induction 4-5%
maintenance 1-2%
Inhalation
2-3 minutes
until disconnected
Ketamine/Valium combination
100mg/ml Ketamine
10 mg/ml Valium
K: 4 mg/kg IV 
V: 0.5-1.0 mg/kg IV
2 minutes
For induction and intubation
Pentobarbital
65mg/ml
25-30mg/kg IV
2 minutes
30-40 minutes
Thiopental (Pentothal)
4% 40mg/ml
20mg /kg IV
2 minutes
15 minutes

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