Department of Laboratory Animal Resources - Medical Care
Use of Analgesics, Tranquilizers, and Anesthetic Agents in Laboratory Animals
|
Rabbit Anesthesia
|
|
Anesthesia
|
Concentration
|
Dose and Route
|
Onset
|
Duration of Surgical Anesthesia
|
Rabbit Cocktail
(ketamine, xylazine and acepromazine) |
42.8mg/ml
1.4mg/ml
8.5mg/ml |
1ml/1.5kg IM |
5-10 minutes |
30 minutes |
Pentobarbital |
65mg/ml |
28mg/kg IV |
1-2 minutes |
30-45 minutes |
Isoflurane
(need precision vaporizer to deliver
the agent) |
induction 4-5%
maintenance 1-2% |
Inhalation |
2-3 minutes |
until discontinued |
Halothane
(need precision vaporizer to deliver
the agent) |
induction 4-5%
maintenance 1-2% |
Inhalation |
2-3 minutes |
until discontinued |
Ketamine
(sedative not analgesic) |
100mg/ml |
44mg/kg IM
15-20mg/kg IV |
5-10 minutes |
20 minutes |
Ketamine and
Diazepam
Valium (Diazepam) |
100mg/ml
10mg/ml |
K: 25mg/kg
IM
D: 5mg/kg IM |
5-10 minutes |
20-30 minutes |
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