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© 1997-2005
Updated 02 May 2005.
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Updated 15 July 2005


Department of Laboratory Animal Resources - Medical Care

Use of Analgesics, Tranquilizers, and Anesthetic Agents in Laboratory Animals

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Canine Analgesics
Analgesic
Brand Name
Concentration
Dose and Route
Frequency
Aspirin
Various
Adult = 325mg/tablet
10-25mg/kg PO
every 8-12 hrs 
Buprenorphine
Buprenex
0.3mg/ml
0.01-0.02mg/kg SC, IM
every 8-12 hrs 
Butorphanol
Torbugesic
10mg/ml
0.2-1.2mg/kg SC, IM
0.05-0.2mg/kg IV
every 2-5 hrs 
Ketoprofen
Orudis
Ketofen
50mg/tablet
100mg/ml
1mg/kg PO, IV
every 24 hrs 
Nalbuphine
Nubain
10mg/ml
0.5-2.0mg/kg
SC, IM, IV
every 3-8 hrs 
Phenylbutazone
Butazolidin
100mg/tablet
15-22mg/kg PO 
**not to exceed 800mg/day
every 8-12 hrs 
Rimadyl
Carprofen
various sizes
1mg/lb PO
2.2mg/kg
every 12 hrs 
Fentanyl patch
(sustained analgesia)
25µ gm patch for dogs <10kg,
50µ gm patch for dogs 10-20kg
75µ gm patch for dogs 20-30kg
100 µ gm patch for dogs >30kg. 
Shave an area on the dorsal neck and
apply the patch. Cover with vetwrap.
*Apply patch 24 hr prior to surgery to reach steady state. 
Remove patch 3-5 days after date of
application.

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