Department of Laboratory Animal Resources - Medical Care
Use of Analgesics, Tranquilizers, and Anesthetic Agents in Laboratory Animals
Anesthetic Cocktails (Xylazine/Ketamine combinations)
|
Species
|
Concentration of mixture
(mg/ml)
|
Dosage
(mg/kg BW ) *
|
Dose and Route
(unit of BW) *
|
| |
ketamine
|
xylazine
|
acepromazine
|
ketamine
|
xylazine
|
acepromazine
|
|
Cat
Ferret
|
50.0
|
7.1
|
2.1
|
11.2
|
1.6
|
0.5
|
Cat - 1ml/10 lbs IM
Ferret - 1ml/14.5kg
|
Dog
|
50.0
|
7.1
|
2.1
|
3.7
|
0.5
|
0.2
|
1ml/30 lbs IV
1ml/14.0kg
|
Goat
Sheep
|
47.6
|
4.8
|
4.8
|
1.8
|
0.2
|
0.2
|
1ml/ 60 lbs IV
1ml/28kg
|
Mouse
Gerbil
|
30.0
|
4.0
|
---
|
120-240
|
16-32
|
---
|
Mouse - 0.1-0.2ml/25gm IP
Gerbil - 0.3-0.6ml 75gm IP
|
Pig
Mini Pig
|
83.3
|
16.7
|
---
|
10.4
|
2.1
|
---
|
1 ml/ 8 kg IM
|
Rabbit
|
42.9
|
8.5
|
1.4
|
28.6
|
5.7
|
1.0
|
1ml / 1.5 kg IM
|
Rat
Guinea Pig
Hamster
|
60.0
|
8.0
|
---
|
24-48
|
3.2-6.4
|
---
|
Rat - 0.1-0.2ml/250gm IP
G.P. - 0.2-0.4ml/500gm IP,IM
Hamster - 0.05-0.1ml/125gm IP,
IM
|