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© 1997-2005
Updated 02 May 2005.
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Updated 15 July 2005


Department of Laboratory Animal Resources - Medical Care

Use of Analgesics, Tranquilizers, and Anesthetic Agents in Laboratory Animals

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Anesthetic Cocktails (Xylazine/Ketamine combinations)
Species
Concentration of mixture (mg/ml)
Dosage (mg/kg BW ) *
Dose and Route (unit of BW) *
 
ketamine
 xylazine
acepromazine
ketamine
xylazine
acepromazine
 
Cat
Ferret
50.0
7.1
2.1
11.2
1.6
0.5
Cat - 1ml/10 lbs IM
Ferret - 1ml/14.5kg
Dog
50.0
7.1
2.1
3.7
0.5
0.2
1ml/30 lbs IV
1ml/14.0kg
Goat
Sheep
47.6
4.8
4.8
1.8
0.2
0.2
1ml/ 60 lbs IV 1ml/28kg
Mouse
Gerbil
30.0
4.0
---
120-240
16-32
---
Mouse - 0.1-0.2ml/25gm IP
Gerbil - 0.3-0.6ml 75gm IP
Pig Mini Pig
83.3
16.7
---
10.4
2.1
---
1 ml/ 8 kg IM
Rabbit
42.9
8.5
1.4
28.6
5.7
1.0
1ml / 1.5 kg IM
Rat
Guinea Pig
Hamster
60.0
8.0
---
24-48
3.2-6.4
---
Rat - 0.1-0.2ml/250gm IP
G.P. - 0.2-0.4ml/500gm IP,IM
Hamster - 0.05-0.1ml/125gm IP, IM